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Confocal microscopy may help identify biomarkers for chemotherapy-induced neuropathy
A University of Arizona Comprehensive Cancer Center researcher received a $2.4 million National Cancer Institute grant to develop a noninvasive, confocal microscope to examine nerve endings of cancer patients with chemotherapy-induced peripheral neuropathy in the hopes of identifying potential biomarkers for the disease.
Residual inflammation can linger in psoriasis patients despite skin treatment
New research shows that in patients with psoriasis, even though their skin responds well to treatment with biologics, inflammation can linger, leading to broader health implications such as obesity and cardiovascular and fatty liver disease.
Study reveals how PAX3 protein drives melanoma growth
PAX3 is a transcription factor (proteins involved in converting DNA into RNA) that drives melanoma progression by promoting cell growth, migration and survival, while inhibiting cellular terminal differentiation, which is the final stage where a cell becomes specialized and cell division ends.
Skin microbiome plays active role in sun protection and immune balance
The skin microbiome plays an important role in health and disease. Researchers have now substantiated that certain skin bacteria can protect us from the sun's ultraviolet (UV) radiation specifically by metabolizing cis-urocanic acid using an enzyme called urocanase.
Why skin shame matters more than symptoms in chronic skin conditions
A new study in Scientific Reports reveals that skin shame is a key psychological burden for people with atopic dermatitis and psoriasis. It significantly affects quality of life, even more than anxiety or depression, especially when disease severity is high.
Terahertz imaging reveals cochlear structures with high resolution
Researchers have discovered a groundbreaking use of terahertz (THz) imaging to visualize cochlear structures in mice, offering non-invasive, high-resolution diagnostics. By creating 3D reconstructions, this technology opens new possibilities for diagnosing hearing loss and other conditions.
Stanford study reveals glucose's surprising role in cell differentiation
The sugar glucose, which is the main source of energy in almost every living cell, has been revealed in a Stanford Medicine study to also be a master regulator of tissue differentiation - the process by which stem cells give rise to specialized cells that make up all the body's tissues.
NIH researchers define topical steroid withdrawal diagnostic criteria
Researchers at the National Institutes of Health (NIH) have determined that dermatitis resulting from topical steroid withdrawal (TSW) is distinct from eczema and is caused by an excess of an essential chemical compound in the body.
Examining skin cancer risk perceptions and reported sunburns among U.S. adults
Skin cancer is the most common cancer in the United States and a significant health issue, with millions of non-melanoma cases and tens of thousands of melanomas diagnosed annually. Furthermore, treating skin cancer costs the U.S. approximately $8.9 billion annually.
Study questions the health benefits of red wine over white wine
A common perception is that not all alcoholic beverages are alike. Red wine, for instance, is often considered a healthier choice, with many believing its high resveratrol content - an antioxidant with anti-inflammatory properties - offers protection against cancer.
Granzyme K identified as key trigger of complement system in autoimmune diseases
Our immune system is armed with an array of defenses designed to detect and eliminate harmful threats. One of its most powerful defense mechanisms is the complement system-a group of proteins that patrols our body, ever vigilant for signs of infection or injury
Exploring the psychological impact of "topical steroid withdrawal"
Painful skin and trouble sleeping are among the problems reported when tapering cortisone cream for atopic eczema. This has been shown by a study headed by the University of Gothenburg. Many users consider the problems to be caused by cortisone dependence.