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Mentavi study validates first fully digital diagnostic pathway for adult ADHD
Mentavi Health announced that its landmark, real-world validation study of the Mentavi Diagnostic Evaluation has been published in the peer-reviewed Journal of Clinical Psychiatry (JCP), a widely read and respected journal.
Global climate warming fuels rising dengue burden across Asia and the Americas
Warmer weather across the globe is reshaping the landscape of human health. Case in point: dengue fever, a mosquito-borne disease once confined largely to the tropics which often brings flu-like symptoms and without proper medical care can escalate to severe bleeding, organ failure, and even death.
‘Rogue’ DNA rings identified as drivers of aggressive brain cancer
An international team of scientists has revealed how rogue rings of DNA that float outside of our chromosomes – known as extrachromosomal DNA, or ecDNA – can drive the growth of a large proportion of glioblastomas, the most common and aggressive adult brain cancer.
Innovative approach advances equity in health care AI
A team of researchers at the Icahn School of Medicine at Mount Sinai has developed a new method to identify and reduce biases in datasets used to train machine-learning algorithms-addressing a critical issue that can affect diagnostic accuracy and treatment decisions.
Study finds universal rise in cholesterol after menopause among Bolivian Tsimane women
Deep in the Bolivian Amazon exists a forager-horticultural community called the Tsimane. Researchers look to them for insights on how the human body functioned prior to modern technologies, as their lifestyles remain the closest to that of our ancestors.
Generative AI creates life-saving antibiotics from scratch
What if generative AI could design life-saving antibiotics, not just art and text? In a new Cell Biomaterials paper, Penn researchers introduce AMP-Diffusion, a generative AI tool used to create tens of thousands of new antimicrobial peptides (AMPs) - short strings of amino acids, the building blocks of proteins - with bacteria-killing potential.
Breakthrough reveals how viruses efficiently pack genetic material
Researchers at San Diego State University and Michigan State University are shedding new light on how viruses meticulously pack their genetic material - a breakthrough that could help researchers engineer antivirals and gene therapies.
Genetic evidence reveals global patterns of language change
Throughout human history, there have been many instances where two populations came into contact – especially in the past few thousand years because of large-scale migrations as a consequence of conquests, colonialization, and, more recently, globalization.
Camena Bioscience and Constructive Bio join synthetic biology collaboration to develop plant genomics
Camena Bioscience (Camena), an innovator in enzymatic DNA synthesis, and Constructive Bio (Constructive), a pioneer in whole genome writing, today announced they have joined a collaborative project led by the Max-Planck Institute of Molecular Plant Physiology (MPI-MP), Germany, for a research initiative to develop synthetic chloroplast genomes.
Early puberty and childbirth tied to accelerated aging and higher disease risk
Reproductive timing matters when it comes to aging and age-related disease. In a study now online at eLife¸ Buck researchers determine that girls who go through puberty (the onset of menstruation) before the age of 11 or women who give birth before the age of 21 have double the risk of developing type 2 diabetes, heart failure and obesity and quadruple the risk of developing severe metabolic disorders.
AI detects early signs of laryngeal cancer from voice recordings
Cancer of the voice box or larynx is an important public health burden. In 2021, there were an estimated 1.1 million cases of laryngeal cancer worldwide, and approximately 100,000 people died from it. Risk factors include smoking, alcohol abuse, and infection with human papillomavirus.
How shifting landscapes drive new bird flu threats across Asia
Landscape changes across the East Asian–Australasian Flyway have reshaped waterfowl migration, increasing interactions with poultry. This shift amplified cross-species viral transmission and raised the risk of avian influenza virus reassortment and diversification.
Balancing copper antimicrobials to combat antibiotic resistance
Copper has emerged as an ally in the battle against antibiotic-resistant bacteria. Copper sulfate liquids, for example, have been used since the 1700s to control fungal infections in vineyards, orchards and many other kinds of agricultural settings.
Programmable Chromosome Engineering systems enable precise DNA manipulations
A team of Chinese researchers led by Prof. GAO Caixia from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences has developed two new genome editing technologies, known collectively as Programmable Chromosome Engineering (PCE) systems.
Starfish compound overcomes drug resistance in prostate cancer models
Researchers identified that triterpene glycosides from the starfish Solaster pacificus can kill drug-resistant prostate cancer cells in vitro by bypassing common resistance pathways. CuC1 showed synergy with existing chemotherapies, though with only moderate selectivity for cancer cells.
New study reveals gaps in research on environmental antibiotic resistance
Antibiotic resistance in the environment is a growing and largely overlooked crisis receiving inconsistent attention, that may very well have dire consequences for human health, according to a new study led by the University of Surrey.
Scientists open new atlas of genetic diversity with advanced sequencing
A global team mapped over 100,000 structural variants in human genomes by applying Oxford Nanopore long-read sequencing and a novel graph-based analytical approach to samples from 26 populations. The study reveals the extraordinary complexity and diversity of human DNA, providing an open-access atlas that will accelerate discoveries in genetic disease and human evolution.