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AI-powered BEACON platform enhances global disease surveillance
The Biothreats Emergence, Analysis and Communications Network (BEACON) leverages advanced artificial intelligence (AI), large language models (LLMs) and a network of globally based experts to rapidly collect, analyze, and disseminate information on emerging infectious diseases affecting humans, animals, and the environment.
H5N1's evolutionary leap could undermine vaccines and heighten human infection risk
From egg prices to pet food recalls – and now, confirmation that another strain of bird flu has infected a large commercial flock of broiler chickens on a Mississippi farm – headlines are capturing escalating concern over H5N1's spread.
Expansion of mutant blood cells linked to worse cancer outcomes
Researchers from the Francis Crick Institute, UCL, Gustave Roussy and Memorial Sloan Kettering Cancer Center (MSK), have discovered that expansion of mutant blood cells, a phenomenon linked to aging, can be found in cancerous tumors, and this is associated with worse outcomes for patients.
Inherited genetic variants play crucial role in cancer development and behavior
A new multicenter study by researchers at the Icahn School of Medicine at Mount Sinai, in collaboration with the National Cancer Institute-funded Clinical Proteomic Tumor Analysis Consortium (CPTAC) and colleagues around the world, has discovered that the genes we are born with-known as germline genetic variants-play a powerful, underappreciated role in how cancer develops and behaves.
Decoding the enzymatic breakdown of alginates for green biotechnology
Every year, thousands of tonnes of brown algae are extracted from the seabed to obtain compounds such as alginates, a polymer composed of sugars that has high density and strength, offering potential biotechnological applications.
Unexpected function of gene network in gut microbes revealed
Could a gene regulatory network in gut microbes have evolved its elaborate and tightly regulated molecular machinery only to pump out antibiotics indiscriminately? Researchers from the Institute of Science and Technology Austria (ISTA) show this is an auxiliary function.
Study uncovers conserved development and evolutionary innovations in the human hypothalamus
In a new study published in Developmental Cell on April 8, a research team led by Prof. WU Qingfeng at the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences has demonstrated the conserved cellular development and evolutionary innovations in the developing human hypothalamus.
Small molecular shifts can drastically alter encephalitis virus behavior
New research shows how small shifts in the molecular makeup of a virus can profoundly alter its fate. These shifts could turn a deadly pathogen into a harmless bug or supercharge a relatively benign virus, influencing its ability to infect humans and cause dangerous outbreaks.
Northwestern scientists develop rapid HIV test for point-of-care diagnosis
A team of Northwestern University scientists spanning disciplines have developed new technology that could lead to the creation of a rapid point-of-care test for HIV infection competitive with traditional lab-based HIV testing in a fraction of the time and without the need for a stressful wait while results are processed or confirmed in a clinical laboratory.
Novel insights into tumor microenvironment and gastric cancer therapy
A team of Singapore scientists has made a significant discovery in understanding stomach cancer, a disease that remains one of the deadliest cancers worldwide. By using advanced mapping technologies, they created a detailed "atlas" of stomach tumors, revealing hidden patterns in how cancer cells behave, evolve and interact with their environment. These insights could lead to more precise, targeted treatments that improve survival rates and reduce side effects.
INTEGRA Biosciences details the evolution and future of serological pipetting
INTEGRA Biosciences has played a pivotal role in advancing the field of serological pipetting over the last 40 years, and has just created a fascinating article covering the fast-paced history of serological pipet controller development.