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6 | Follower
Based on the findings of two meta-analyses and several large cohort studies, we cannot conclude that cannabis is “safe” for use during pregnancy. Data regarding risk for autism spectrum disorder is mixed.
Because women with bipolar disorder are at high risk for relapse during the postpartum period, we typically recommend that women continue treatment with lithium throughout the postpartum period. While this intervention clearly decreases risk for postpartum psychiatric illness, the use of lithium while breastfeeding presents certain challenges.
In this study with over 4000 infants exposed to gabapentin, the information is reassuring. While we cannot rule out the possibility of a small increase in risk of cardiovascular malformations in gabapentin-exposed infants, gabapentin does not appear to be a major teratogen.
The psychostimulant lisdexamfetamine was well-tolerated and improved both subjective and objective measures of attention and working memory in women undergoing surgical menopause.
With ketamine and esketamine increasingly used to treat depression, especially in women of reproductive age, this study reveals important gaps in care, including inconsistencies in pregnancy testing, informed consent, and contraception practices among ketamine clinics in the United States.
In this large observational study, similar and, in some instances, more favorable neonatal and maternal outcomes were observed in pregnancies exposed to buprenorphine combined with naloxone compared to pregnancies exposed to buprenorphine alone.
This study provides valuable insight into the inequities in perinatal mental healthcare and suggests that the most significant barriers to mental healthcare may occur at the provider referral level.
Clinically significant anxiety symptoms are common during the postpartum period and frequently complicate the treatment of postpartum depression. While SSRIs are indicted for the treatment anxiety symptoms, especially when they co-occur with depression, many women may need to use a benzodiazepine for managing more severe symptoms of anxiety or insomnia.
This large cohort study from Taiwan indicates that the concomitant use of antidepressants and benzodiazepines during the first trimester is not associated with a substantial increase in risk for overall malformations.
A New Drug Application was submitted to the FDA for a novel, nonhormonal dual neurokinin-1 and neurokinin-3 receptor antagonist for the treatment of menopause-related vasomotor symptoms.
This review and meta-analysis reviews the effectiveness of cognitive behavioral therapy and mindfulness interventions for depression, anxiety, and cognitive functioning in women undergoing menopausal transition.
Dr. Lee S. Cohen, Director of the Ammon-Pinizzotto Center for Women's Mental Health at Massachusetts General Hospital, recently shared his insights on access to perinatal mental healthcare with Ob.Gyn News on May 23, 2024.
A growing body of literature supports the reproductive safety of stimulants in pregnant women and suggests that not treating may have negative consequences for the mother and her child.