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Over-the-counter (OTC) products like St John’s Wort and omega-3s have long been touted for helping with depression, but new research reveals that 64 different OTC products have been tested in clinical trials, with varying levels of evidence. Some well-known options like St John’s Wort, saffron, and probiotics showed encouraging results, sometimes comparable to antidepressants. Others like folic acid, lavender, and lemon balm show emerging promise. Although few safety concerns were reported, researchers stress the need for better safety reporting and more studies, especially on commonly used but understudied herbal remedies.
President Trump s diagnosis of Chronic Venous Insufficiency (CVI) has brought renewed attention to a frequently overlooked yet dangerous condition. CVI affects the ability of veins especially in the legs to return blood to the heart, often leading to swelling, pain, skin changes, and ulcers. The American Heart Association warns that CVI isn t just a cosmetic issue; it's strongly linked to cardiovascular disease and increased mortality, even when other risk factors are accounted for. Seniors, smokers, those with sedentary lifestyles, and people with obesity are particularly at risk.
A mysterious gut hormone may be behind many cases of chronic diarrhea, especially in people with undiagnosed bile acid malabsorption, a condition often mistaken for irritable bowel syndrome. Researchers from the University of Cambridge identified that the hormone INSL5 spikes when bile acid reaches the colon, triggering intense diarrhea. Their discovery not only sheds light on the biological cause of symptoms but opens the door to a diagnostic blood test and new treatment options, including a surprising existing drug that blocks this hormone’s effects.
Medieval medicine is undergoing a reputation makeover. New research reveals that far from being stuck in superstition, early Europeans actively explored healing practices based on nature, observation, and practical experience—some of which uncannily echo today’s wellness trends on TikTok.
Yoga, Tai Chi, walking, and jogging may be some of the best natural remedies for improving sleep and tackling insomnia, according to a large analysis comparing various treatments. While cognitive behavioral therapy (CBT) remains effective, exercise-based approaches—especially Tai Chi—were shown to deliver significant improvements in total sleep time, efficiency, and reducing how long people stay awake after falling asleep. Yoga stood out for boosting overall restfulness, and jogging helped ease insomnia symptoms.
Fermenting stevia with a banana leaf-derived probiotic turns it into a powerful cancer-fighting agent that kills pancreatic cancer cells while sparing healthy ones. The secret lies in a metabolite called CAME, produced through microbial transformation.
What if your brain is the reason some pain feels unbearable? Scientists at the Salk Institute have discovered a hidden brain circuit that gives pain its emotional punch—essentially transforming ordinary discomfort into lasting misery. This breakthrough sheds light on why some people suffer more intensely than others from conditions like fibromyalgia, migraines, and PTSD. By identifying the exact group of neurons that link physical pain to emotional suffering, the researchers may have found a new target for treating chronic pain—without relying on addictive medications.
Swap steaks for spinach and you might watch the scale plummet. In a 16-week crossover study, overweight adults who ditched animal products for a low-fat vegan menu saw their bodies become less acidic and dropped an average of 13 pounds—while the Mediterranean diet left weight unchanged. Researchers link the shift to lower “dietary acid load,” a hidden inflammation trigger driven by meat, eggs, and cheese.
A groundbreaking wireless implant promises real-time, personalized pain relief using AI and ultrasound power no batteries, no wires, and no opioids. Designed by USC and UCLA engineers, it reads brain signals, adapts on the fly, and bends naturally with your spine.
A new study is turning heads by challenging the popular belief that seed oils are harmful to health. Researchers analyzed blood markers from nearly 1,900 people and found that higher levels of linoleic acid — an omega-6 fat commonly found in seed oils — were linked to lower inflammation and better cardiometabolic health. The study used direct biomarkers instead of diet surveys, making its findings more robust. These results support a growing body of evidence that seed oils, far from fueling disease, may actually help protect against heart disease and type 2 diabetes.
Up to 25% of new mothers suffer from postpartum depression, which can significantly impact their parenting behavior and the wellbeing of their children. A new study looks at long-term effects of early maternal depression on children, underscoring the need to provide adequate support for mothers who might be struggling.
Irritable bowel syndrome (IBS) is a common digestive disorder with unclear causes, affecting about 10% of the global population. Researchers have now discovered that opioid delta-receptor agonists may alleviate IBS symptoms by acting directly on the central nervous system. Using a novel stress-induced mouse model, they found these drugs reduce abdominal pain and regulate bowel movements. This research suggests a promising approach to treating IBS by targeting stress as a contributing factor.
A special liquid diet, known as exclusive enteral nutrition, is an essential therapy for Crohn's disease. Patients consume only this formula for six to eight weeks, completely avoiding solid foods. However, the exact reasons why this is helpful were previously unclear. Researchers have now been able to decipher the mechanism behind this dietary therapy.
Psoriasis is a chronic skin disease that manifests itself mainly with skin symptoms (dryness, itching, scaly skin, abnormal patches and plaques). It affects about 2% of the population and is mediated by an altered immune system response that triggers the proliferation of skin cells. Depending on the severity, there are different therapeutic options (topical medications, phototherapy, systemic drugs, etc.), but some conventional treatments can have harmful effects on patients.
People who were less active, with a daily average of more than 14 hours of sedentary behavior, were more than twice as likely to have another cardiac event, including heart attack, surgery to treat heart issues (coronary revascularization), or to be hospitalized again within a year after the first cardiac event.
Saying one thing while feeling another is part of being human, but bottling up emotions can have serious psychological consequences like anxiety or panic attacks. To help health care providers tell the difference, a team has created a stretchable, rechargeable sticker that can detect real emotions -- by measuring things like skin temperature and heart rate -- even when users put on a brave face.
A novel analysis of more than 375 published studies concluded that the association between chronic pain and rates of depression and anxiety is staggering. The study found that 40% of adults with chronic pain experienced 'clinically significant depression and anxiety.' Among those most at risk, the analysis showed, were women, younger adults and people with fibromyalgia.
Identifying and treating risk factors for depression, anxiety and other psychological health conditions during pregnancy and postpartum may improve short- and long-term health outcomes for both mother and child, according to a new scientific statement.
A daily intake of one gram of omega-3s can slow down biological aging by up to four months, according to an analysis of clinical data from the international DO-HEALTH study. For the first time, epigenetic clocks were used to measure the aging process.
Higher levels of the minerals copper and manganese in pregnant women were associated with lower blood pressure and a reduced risk of developing high blood pressure decades later, according to a long-term study.
Scientists examined the bitterness intensity of five medicines and two bitter modifiers in 338 adults of European descent and recent US and Canadian immigrants from Asia, South Asia, and Africa. Bitterness ratings differed by ancestry for two of the five drugs and the effectiveness of some modifiers. They also found genetic variants that explain some population differences in reaction to bitter tastes.
New research shows that a network of subcellular structures similar to those responsible for propagating molecular signals that make muscles contract are also responsible for transmitting signals in the brain that may facilitate learning and memory.
Groundbreaking device instantly detects dangerous street drugs, offering hope for harm reduction A portable device that instantly detects illicit street drugs at very low concentrations, thereby highlighting the risks they pose. The device has the potential to address the growing global problem of people unknowingly taking drugs that have been mixed with undeclared substances, including synthetic opioids such as fentanyl and nitazenes.
Researchers have uncovered how perceptual memories linked to positive emotions, such as joy or happiness, are strengthened during sleep. The study could help scientists understand the neurological basis for overcoming conditions like drug addiction.
Researchers demonstrated that brewing tea naturally adsorbs heavy metals like lead and cadmium, effectively filtering dangerous contaminants out of drinks. Researchers tested different types of tea, tea bags and brewing methods. Finely ground black tea leaves performed best at removing toxic heavy metals. Longer steeping times helped tea remove larger amounts of contaminants.
Oral mucositis is a painful condition in which the mucous membranes inside the mouth become inflamed. To help alleviate this, researchers have developed a mucoadhesive film using xyloglucan and antioxidant-rich green tea extract containing catechins. With its strong adhesive properties, the film directly adheres to the affected area. Made from accessible ingredients, this solution could provide localized relief and improve the quality of life for patients.