News
Entertainment
Science & Technology
Life
Culture & Art
Hobbies
News
Entertainment
Science & Technology
Culture & Art
Hobbies
Depression is a serious mental health condition that can have a significant impact on a person's life. It can affect a person's ability to work, socialize and maintain relationships. Fortunately, there are a number of treatments available that can help individuals manage their symptoms and lead a healthy life. This category includes news and articles about depression, as well as videos and interviews with experts in the field.
I det senaste avsnittet av podden Vi bygger landet presenteras och diskuteras Ernst Wigforss bidrag till arbetarrörelsens kamp för full sysselsättning och den ekonomiska politiken. Väl värt att lysssna på! Ernst Wigforss kunde som Sveriges finansminister under stora delar av mellankrigstiden och de tidiga åren efter andra världskriget bidra till att omvandla Sverige till en…
Rain lashed most parts of Odisha on Saturday even as the low-pressure area over the Bay of Bengal intensified into a depression, the IMD said.Of the 30 districts of Odisha, 26 districts have experienced rainfall in the last 24 hours till 8.30 am on Saturday. Get more India News and Business News on Zee Business.
As fireworks marked the beginning of 2023, Virginia Woolf’s novel To the Lighthouse was finally released from US copyright. To mark the occasion I reprise a lightly edited and amplified version of a column which first appeared in the Financial Times in 2002. The year is 1927, and Virginia Stephen is talking to her husband, Leonard Woolf, over the cornflakes in their elegant Bloomsbury home. VIRGINIA: Darling, I am thinking of writing a novel called To the Lighthouse, based on experiences in my family childhood, and set on the Isle of Skye. It will be a masterpiece of 20th-century fiction. LEONARD: What a good idea, darling. With the Great Depression about to start, the royalties will come in handy. We will not only be able to afford the groceries, but enrich the children and grandchildren of our nephew. The following morning: VIRGINIA: Leonard, my agent tells me that under British law, copyright in my new work will expire 50 years after my tragic suicide in 1941. Wordsworth Editions will then be free to produce copies of To the Lighthouse and will sell them for as little as £1. Students will even be able to buy annotated editions to help them with their exams. (Both aesthetes grimace in horror at the prospect.) LEONARD: What a blow to our finances! But what can we expect in a country governed by men such as Ramsay Macdonald and Stanley Baldwin, with no understanding of the economic needs of creative people? A week later: VIRGINIA: Leonard, my agent has just learned that a European directive which will be approved in 1993 will extend copyright in my work for 20 years. And – what joy – Congress will pass a law in 1998 prolonging my US rights for 75 years after initial publication. I am to be spared the degradation of my books appearing in Walmart until two decades of the next millennium! LEONARD: Wonderful news, Virginia. And how fortunate that our friend Maynard Keynes is coming for dinner. He is a director of the Midland Bank and I am sure that as well as warning us about the impending depression and the collapse of the gold standard, he can arrange a loan on the security of the royalties you will earn between 1991 and 2022. I will pop out to the stationer and buy you pen and ink right away. And so British novelists and composers who died more than 50, but less than 70, years ago were able to leave their footprints in the sands of time. But for the prospect of retrospective copyright extension we could so easily have lost not just To the Lighthouse, but 1984 (published 1949, Orwell died 1950) and The Grapes of Wrath (published 1939, Steinbeck died 1968). How fortunate we are that Jane Austen, Herman Melville and DH Lawrence were not deterred from writing by the short copyright terms prevailing when they wrote! Copyright on The Grapes of Wrath, perhaps the greatest novel of 1930s depression America, will expire in the US in 2034 and in Europe in 2038. The Great Gatsby, the iconic novel of the roaring twenties, entered the public domain only last year. In 2003 the US Supreme Court decision upheld the 1998 extension of copyright (legislation officially called the Sonny Bono Copyright Act after the chart topping singer – I’ve Got You Babe – turned Representative from California, but more widely known as the Mickey Mouse Copyright Act after the Disney Corporation lobbied vigorously for its passage.) Dissenting, the sadly missed Justice Stephen Breyer noted the minimal present value of earnings 95 years in the future and asked “What potential Shakespeare, Wharton, or Hemingway would be moved by such a sum? What monetarily motivated Melville would not realize that he could do better for his grandchildren by putting a few dollars into an interest-bearing bank account?” Has any company’s discounted cash-flow calculation ever incorporated returns more than 75 years from now? The retrospective nature of the change in the law shows that the object is not to stimulate new creative activities but to enrich owners of the rights to old ones. Breyer observed that the Constitution allowed Congress to pass legislation to “promote the Progress of Science . . . by securing for limited Times to Authors . . . the exclusive Right to their respective Writings. That was not the motive which prompted the Mickey Mouse Act. (However the Majority on the Court took the view that the meaning of ‘limited Times’ was a subject within the proper scope of Congressional judgment.) Now there is something in the argument that a single powerful company is the best means of securing investment in, and development of, products and activities. But the experience of modern market economies is that innovation and consumer interests are almost always better served by competition than monopoly. Creative industries differ only in that diversity and experiment are even more important in art and literature than in oil and water supply. Shakespeare’s legacy might be better protected and developed if his works and characters could only be used under license from the Royal Shakespeare Corporation. Such an agency could prohibit bad productions and ensure that annotated texts properly reflect the consensus of the corporation’s approved scholars. But the history of totalitarian art gives little grounds for optimism that this would stimulate creativity. Rather the opposite.
Tweet… is from page viii of Douglas Irwin’s 2012 book, Trade Policy Disaster: Lessons from the 1930s: The worst nightmare of every trade economist is that, in the midst of an economic crisis, policymakers might be tempted to return to the autarkic, beggar-thy-neighbor protectionism of the Great Depression. Such a move, it is feared, could […]
Shares of Sage Therapeutics Inc. (SAGE) surged over 45% to $8.09 in after-hours trading on Friday following an unsolicited, nonbinding acquisition proposal from Biogen Inc. (BIIB).Biogen has proposed to acquire all the remaining common shares of Sage Therapeutics it does not yet possess, at a rate of $7.22 per share. According to a recent SEC filing, Biogen currently holds a 10.2% stake in Sage.The strategic partnership between Sage and Biogen commenced in 2020. In November of that year, the two companies agreed to collaborate on the development and commercialization of SAGE-217 and SAGE-324. As part of this agreement, Biogen acquired approximately 6.24 million shares of Sage at an average price of $104.14 per share on December 31, 2020, totaling around $650 million.SAGE-217 gained regulatory approval in August 2023, distinguishing itself as the first FDA-approved oral medication for postpartum depression, marketed under the brand name Zurzuvae. Meanwhile, collaboration on another project, SAGE-324, encountered substantial obstacles.In July 2024, the KINETIC 2 phase IIb study of SAGE-324 for Essential Tremor failed to achieve its primary objectives. Subsequently, Biogen ended its collaboration with Sage concerning SAGE-324 in September 2024.Sage has also faced considerable difficulties with its key drug candidate, Dalzanemdor. In April 2024, Dalzanemdor, or SAGE-718, did not reach its primary goal in a phase II trial for patients with mild cognitive impairment associated with Parkinson's disease, termed PRECEDENT. The setbacks continued through the latter half of 2024, with two additional unsuccessful trials.A phase II trial exploring Dalzanemdor's efficacy in patients with mild cognitive impairment or mild dementia due to Alzheimer's Disease, known as LIGHTWAVE, concluded unsuccessfully in October, followed by another phase II study failing in November 2024 for Huntington's Disease.Regarding the acquisition offer, Sage announced that its Board of Directors will thoroughly assess and deliberate on Biogen's proposal to decide on the appropriate course of action.The company's shares had reached record highs of $195 in January 2018. Over the past year, SAGE's stock price fluctuated between $4.62 and $28.26, closing at $5.55 on Friday, reflecting a 5.13% decline.The material has been provided by InstaForex Company - www.instaforex.com
President Xi Jinping’s government reached last year’s 5% growth target, a well-telegraphed victory that came as little surprise. But a closer look at the numbers reveals a reliance on trade that’s set to inflame US ties. Hours before the official data arrived for China’s fourth quarter, Scott Bessent — Donald Trump’s pick for Treasury secretary — accused the Chinese of “attempting to export their way out” of what he called “a severe recession, if not depression.”
Tweet… is from page xi of George Selgin’s excellent forthcoming (in April) book, False Dawn: The New Deal and the Promise of Recovery, 1933-1947: Of course, the New Deal didn’t end the Great Depression: despite the occasional op-ed or blog post saying otherwise, no competent economic historian thinks so. Nor could any American adult alive […]