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The following are some of the news articles, videos, and other resources related to patient health and wellbeing. 1. Five Ways to Help Your Patients Heal Faster After Surgery: Advice from an Experienced Surgeon 2. The Benefits of Telemedicine: How Technology Is Improving Access to Quality Care 3. Mental Health: Understanding the Behavioral Health Crisis in America 4. How to Choose the Right Healthcare Provider for You 5. How to Manage Chronic Pain: Tips from an Expert 6. The Benefits of Mindfulness Meditation 7. 10 Tips for Eating Healthy on a Budget 8. The Benefits of Exercise for Overall Health 9. How to Talk to Your Doctor About Your Health 10. How to Handle Health Insurance Claims and Denials
Sense Neuro Diagnostics, a startup developing a noninvasive brain scanner to improve outcomes for patients with stroke or brain injuries, is expanding after a partnership with Rochester, Minn.-based Mayo Clinic, Cincinnati Business Inquirer reported.
Rituximab (RTX), a chimeric monoclonal antibody targeting CD20 on B lymphocytes, is an effective disease-modifying agent in the treatment of pemphigus vulgaris (PV), a rare autoimmune blistering disease (AIBD) (Witte et al. 2018; Yuan et al. 2022). PV is caused by serum IgG autoantibodies targeting adhesion molecules of the cadherin family, particularly desmoglein (Dsg)3 and Dsg1, two major components of desmosomes (Spindler and Waschke 2018). PV usually arise with oral erosions first and then spreading to the skin with a chronic-relapsing course (Feliciani et al.
Despite remarkable advances in treating patients with metastatic melanoma, management of melanoma brain metastases remains challenging. Recent evidence suggests that epigenetic reprogramming is an important mechanism for the adaptation of melanoma cells to the brain environment. In this study, methylomes and transcriptomes of a cohort of matched melanoma metastases were evaluated by integrated omics data analysis. The identified 38 candidate genes displayed distinct promoter methylation and corresponding gene expression changes in intracranial compared to extracranial metastases.
Start codon mutations in ubiquitin ligase Kelch-like protein 24 (KLHL24) lead to a gain-of-function mutant KLHL24-ΔN28, which mediates the excessive degradation of keratin 15, desmin, and keratin 14, resulting in alopecia, cardiopathy, and epidermolysis bullosa syndrome (ACES). ACES patients normally present atrophic scars after wounds heal, which is rare in KRT14-related epidermolysis bullosa (EB). The mechanisms underlying the formation of atrophic scars in EB of ACES patients remain unclear. This study demonstrated that KLHL24-ΔN28 impaired skin wound healing by excessively degrading vimentin.
Did You Know? In the United States, food insecurity has been proved to be negatively associated with untreated caries. Pediatric dentists see approximately 40% of patients aged 2 to 4 years. 54% of kids aged 12–19 have caries. When children have their first dental visit at age 4 years or younger, parents will save an average of $360 in dental care costs over the
Intermountain Healthcare recently partnered with Story Health to help manage patients’ heart failure by increasing access to specialty care. Under the partnership, Intermountain clinicians are working with Story’s health coaches to help patients keep up with their treatment plans while they’re outside the walls of the doctor’s office.