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- Natural Health Mar 30, 2017 · Treatment. Treating sciatica is a combination of several approaches. Generally, anti-inflammatory medications are the first line of treatment. Nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen or naproxen, may be recommended to help reduce pain and inflammation. Latest News and Research on Sciatica - News Medical Mar 27, 2017 · Latest News and Research on Sciatica Sciatica is a common form of low back and leg pain that radiates from the sciatic nerve, the largest nerve in the body. Sciatica: Symptoms, Treatment & Exercises - MedicineNet Sciatica is a medical condition characterized by pain going down the leg from the lower back. This pain may go down the back, outside, or front of the leg. Onset is often sudden following activities like heavy lifting, though gradual onset may also occur. Sciatica - Diagnosis and treatment - Mayo Clinic Treatment. Sciatica is typically treated conservatively, and surgery is only recommended in rare cases. Initially, your doctor will likely recommend one or more of the following treatments: Heat or ice. Apply