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Mapmygenome's pioneering longevity study on Indians living over 85 reveals fascinating genetic secrets. Discoveries include variants linked to slower heart rate, short height, disease protection, and the FOX03A gene, offering valuable insights into longevity within the Indian population.
For years the metabolic cart was considered the gold standard for measurement of resting metabolic rate. However, due to their inaccuracy and anxiety of people being placed under the ventilated hood, they are fast moving aside for the new gold standard in town...whole room indirect calorimetry.
In this Q&A, Gina Rippon discusses her research interests relating to the study of female autism. She has recently published a review in the BMC journal Biology of Sex Differences, and her latest book, published by Pan Macmillan and Seal Press (US), will be released in 2025.
Reflections on pharmacy syringe sales for World AIDS Day 2024. A discussion of trends in syringe access and a call for state standing orders for syringes.
Valine specifically binds to the primate-specific SE14 repeat domain of HDAC6, retaining it in the cytoplasm. Valine deprivation triggers HDAC6 nuclear shift, increasing DNA demethylation and damage via TET2 activation. Valine restriction inhibits tumor growth, and enhances the effects of PARPis.
Single amino acid/dipeptide-based system displays periodic changes in assembly and disassembly under non-equilibrium conditions in closed system, particularly in the absence of evolved biocatalysts with the help of feedback loop.
This post reflects on our research on risk perception in Twitter users in Aotearoa New Zealand between August and November 2021, a period of major change in the country’s pandemic response. We found a risk nexus embedded in the vaccine and in those who refused to be vaccinated, not the virus.
We have established a new screening pipeline named CIBER (CRISPR-assisted individually barcoded sEV-based release regulator) screening that enables the massively parallel identification of the release regulators of small extracellular vesicles.
Real-world evidence suggests a potential role of early secondary treatment in prostate cancer with biochemical recurrence after primary therapy.
About 150 years after the first picture of the thalamus by Luys (1873), revealing the centre median nucleus (red), a new advanced architectural description of nuclear and fiber systems of deep brain, relying on MRI, is freely available to the scientific community, in a transdisciplinary approach.
This blog, and the paper, explore the evolution of ‘ndrangheta families in Australia, highlighting four ideal-types. It examines how familial ties, cultural adaptation, and societal influences shape their recognition, reputation, and involvement in organized crime across generations.
the material also showed high absorbance in the wavelengths ranging from 334 to 338 nm, which makes it good for the solar cell applications. Overall, zinc-doped Ba-Ni ferrite is a good candidate for sustainable and renewable energy applications.
The direct conversion of methane into methanol and acetic acid offers a sustainable pathway for producing high-value chemicals. We achieve this transformation by harnessing a multifunctional iron(III) dihydroxyl catalytic species within a MOF framework, using molecular oxygen as the oxidant.
This study found that tropical cyclone-related flood risk shifts from the Mekong Delta to the eastern part of the Lower Mekong Basin, highlighting the importance of tropical cyclone hazards and socio-economic exposures to flood risk.
The enhanced X-ray flux available at light sources worldwide necessitates a step-change in the way crystallographers collect data. We report a small-rotative fixed-target serial synchrotron crystallography method for small molecules, expanding the scope of multi-crystal methods to chemical samples.
Birds’ evolution led to morphological adaptive variations in feet. We use anatomical network analysis to find a constraint foot organization, an evolutionary trend toward simplification, and no association between foot complexity and foot specialization.
In this blog, we will explore the fascinating interplay between the ‘ndrangheta's mobility, its clans' cultural transformations, and the impact of technological advancements particularly when the clans of the Calabrian mafia move.
Using GPU-accelerated state-vector emulation, we propose to embed a quantum computing ansatz into Density Functional Theory to obtain quantitative quantum chemistry results on molecules that would otherwise have required brute-force quantum calculations using far more than 100 logical qubits
Reducing and maintaining body weight are key in tackling obesity, but the body seems to retain a metabolic memory impeding long-term success. Here, we explore this phenomenon and show that cells in human and mouse adipose tissue retain a functional obesogenic memory after substantial weight loss.