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We analysed exhaled metabolites to find endogenous volatile markers indicative of postmenopausal osteoporosis. Our non-invasive breath test served as more rapid and reliable classification of osteoporosis risk while compared to conventional serum bone markers and included markers of gut-bone axis.
Our work presents a new interphase chemistry in which reductive electrophiles gain electrons and cations from solid-state electrolytes upon contact, forming layers on the materials' surfaces, which enhances their electrochemical stability and offers adaptable solutions for other battery materials.
In the quest for sustainable development, scientists are continuously inspired by nature to create innovative technologies. One such breakthrough is featured in a recent paper published in Nature Communications, which introduces the topic of "Room-temperature phosphorescent transparent wood."
Crystal structures of the SAM-utilizing ribozyme, SAMURI, were decoded, revealing the structural features that distinguishes itself from SAM riboswitches and thus enables the alkyl transfer reactions.
A high-valence bismuth(V) nanoplatform has been proposed for the first time for triggering cancer cell death and anti-tumor immune responses via an exogenous excitation-free and endogenous H2O2- and O2-independent reactive oxygen species generation behavior.
By using programmable digital coding metasurface, a dual-channel near-field holographic MIMO communication system is realized in low cost and low system complexity.
A new study investigates the role of a robot’s inner speech in enhancing human phronesis, the ability to make ethically sound decisions, particularly when caring for individuals with special needs. This research marks a significant step toward the development of Artificial Phronesis.
Pantothenate-kinase-associated neurodegeneration (PKAN) is a rare disease caused by pathogenic variants in the PANK2 (pantothenate kinase 2) gene, causing dystonia, rigidity, choreoathetosis, retinal degeneration or optic atrophy, neuropsychiatric abnormalities and early death.
This research explores how elevated green spaces enhance resilience and well-being in hyperdense cities. Using London case studies, it offers insights for designing sustainable, accessible, and inclusive urban spaces. Read more: https://link.springer.com/article/10.1007/s43621-024-00755-9
We found some bioinformatic evidence that lipoxygenase enzyme and oxylipin signalling might empower some bacteria to "jump" between plants and humans. To enforce our hypothesis, I undertook data research. Here, I explain why I have decided to keep it as a formally unpublished preprint.
High-resolution observations and multi-waveband optical constraints from ground-based and satellite data in Xuzhou, China, and Dhaka, Bangladesh, reveal that urban riverbanks and small industrial sites are often overlooked sources of black carbon emissions in Asian cities.
Monocyclic aromatic molecules are well-known in organic chemistry and for coordination chemistry. In contrast, isoelectronic cycles comprising (semi)metal atoms only are much rarer. We present Bi5−, the so far elusive heaviest analogue of (C5H5)− which we trapped in an inverse-sandwich-type complex.
Galois is renowned for his Galois theory of algebraic equations, the creation of group theory, and the dramatic story of his testamentary letter before his fatal duel. Yet, he also outlined an extraordinary and influential theory of ambiguity that deserves attention.
It is known that heatwaves become more severe as the climate warms. But a new study led by the University of Graz now shows that the most extreme heat events may intensify much stronger than previously expected.
This invited blog is based on the publication of our paper Russo, C., et al. Non-invasive screening of breast cancer from fingertip smears—a proof of concept study. Sci Rep 13, 1868 (2023). https://doi.org/10.1038/s41598-023-29036-7 in which was the 4th most downloaded cancer paper in 2023
This prospected research advances an internalist view on the concepts of scientific literacy and effectiveness of science communication to the general public, within an epistemological framework.
The detection of Highly Pathogenic Avian Influenza (HPAI) A(H5N1) in dairy cattle in the United States has raised concerns about human exposure.
What’s in a name? In today’s highly competitive business landscape, branding is becoming increasingly associated with building strong emotional connections between brands and their target audience. But can brand names really carry a subconscious advantage in driving consumer attention?
Our study shows that DLGAP5 enhances gemcitabine resistance in bladder cancer by stabilizing MYC protein via USP11-mediated deubiquitination. This interaction boosts MYC-driven glycolysis, suggesting that targeting the DLGAP5-USP11-MYC axis could overcome resistance.
This study has recently been accepted in Signal Transduction and Targeted Therapy. The study reveals a new immune checkpoint of NK cells functional in the livers, a TM4SF5 and SLAMF7 linkage, and TM4SF5-specific isoxazole-based small molecules inhibitory against the linkage.
Black Bone Chickens (BBCs) are famous for their striking black skin, bones, and tissues, caused by a unique genetic trait. Our study focused on the Id locus, which inhibits pigmentation. Using public datasets, we discovered a rearrangement that explains BBCs unique features and their evolution.
As global temperatures rise, heat-related chronic health disorders are expected to increase. We asked if severe exertional heat stress induces long-term health effects in a mouse model. We found that after a 3 month recovery, mice developed obesity, cardiac hypertrophy and metabolic dysfunction.
Bovine colostrum has become one of the emerging nutraceuticals, and it is being extensively utilized in nutraceuticals and healthcare products in the pre-treatment of numerous chorionic ailments as well as to improve the gut health owing to its nutrient-bioactive rich makeup
Between 60% of hemodialysis patients have hypervolemia. The present study hypothesizes that there is more notable survival in CKD patients whose hypertension can be controlled without antihypertensives and with ongoing dry weight reduction with the point-of-care dry weight (POC-DW) technique.
In our next episode of Nature Water Talks, we explore how observation, involving a combination of conventional and modern techniques that allow for knowledge on the dynamics of water quantity and quality, is the first step towards understanding water resources.
This blog describes an article written about dental care for patients with acquired brain injury, as well as the importance of intravenous conscious sedation as an adjunct.