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Pectolinarigenin inhibits bladder urothelial carcinoma cell proliferation by regulating DNA damage/autophagy pathways | Research Communities by Springer Nature

Pectolinarigenin (PEC) from herbal medicine targets DNA topoisomerase II alpha (TOP2A) in bladder cancer (BLCA), causing DNA damage and blocking cell division. It inhibits autophagy, boosting its effectiveness. Combined with gemcitabine, PEC more effectively halts BLCA growth.

The impact of anger and age on depression | Research Communities by Springer Nature

According to the historical book, Hua Tuo, a doctor, used anger to cure patients with depression. Traditional Chinese medicine theory believes that human emotions influence each other, and one emotion can suppress another emotion and it is applied to clinical practice.

myeloMATCH program opens enrollment for acute myeloid leukemia and MDS

Four leading cancer research organizations in the United States and Canada announce the opening of patient enrollment to myeloMATCH, a unique portfolio of clinical trials to test precision medicine treatments for adults with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS).

New antibody platform targets evolving viruses

Scientists at the Icahn School of Medicine at Mount Sinai, in collaboration with colleagues in the field, have developed an innovative antibody platform aimed at tackling one of the greatest challenges in treating rapidly evolving viruses like SARS-CoV-2: their ability to mutate and evade existing vaccines and therapies.

3D tumor mapping reveals new insights into cancer biology and treatment

A new analysis led by researchers at Washington University School of Medicine in St. Louis has revealed detailed 3D maps of the internal structures of multiple tumor types. These cancer atlases reveal how different tumor cells -; and the cells of a tumor's surrounding environment -; are organized, in 3D, and how that organization changes when a tumor spreads to other organs.

Making multispecific capacity of antibodies into a precision medicine tool | Research Communities by Springer Nature

Behind the scenes of our work to adapt an agonistic antibody with any type of drug cargo in order for us to improve the impact on the immune system and thereby therapeutic efficacy.

Targeted bacteriophages offer standardized and scalable GI therapy

In a new study, researchers at the University of Copenhagen have been cultivating 'good viruses' from feces. The goal is to replace fecal capsules now being used in so-called fecal transplants. Their new technique has shown potential in studies with mice and the hope is that it will improve this life-saving treatment through standardization and pave its way toward mainstream medicine.

The Machine Model in Medicine | Evolution News

The unfortunate fact is, there really are those two conflicting sides in medicine.

Introduction to Gambling Addiction at the Faculty of Medicine and Surgery, University of Rome Tor Vergata, Rome, Italy (July 2019). | Research Communities by Springer Nature

Transforming GBMSM Health: How eHealth is Paving the Way for Better Sexual Health Outcomes | Research Communities by Springer Nature

New research published in npj Digital Medicine shows that an ehealth interactive intervention reduced instances of condomless anal sex by enhancing self-efficacy and attitudes toward condom use among gay, bisexual, and other men who have sex with men.