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Just one mutation can make H5N1 bird flu a threat to humans - Los Angeles Times

The Scripps Research Institute finding counters prevailing thought that the virus would require multiple mutations before it poses a threat to public health.

Scientists identify mutation that could facilitate H5N1 bird flu virus infection and potential transmission in humans

Avian influenza viruses typically require several mutations to adapt and spread among humans, but what happens when just one change can increase the risk of becoming a pandemic virus?

Bovine H5N1 influenza shows potential for human adaptation through key mutations

Recent study reveals H5N1 mutations enhancing human receptor binding, highlighting pandemic risks and the need for vigilant surveillance of influenza strains.

Genetic mutations in parasites may lead to global spread of sleeping sickness

Parasites that cause the deadly illness known as sleeping sickness can spread beyond their native Africa as a result of mutations to key genes, a study shows.

Genetic mutation in esophageal cancer found to have dual effects

A genetic fault long believed to drive the development of esophageal cancer may in fact play a protective role early in the disease, according to new research published in Nature Cancer.

As US marks first H5N1 bird flu death, WHO and CDC say risk remains low - Ars Technica

No human-to-human spread identified and no concerning mutations circulating.

Same Same but Different: Exploring the Rainbow of TP53 Mutations | Research Communities by Springer Nature

Using CRISPR-mediated saturation genome editing, we characterized 9,225 TP53 variants, uncovering diverse effects such as partial loss of function and splicing disruptions, offering new insights into p53 dysfunction and advancing cancer prognosis and therapy development.

Unveiling FLT3-JMD Point Mutations in AML: A Rare Yet Pivotal Subtype | Research Communities by Springer Nature

Researchers uncover new mutation mechanism driving cancer progression

Osteosarcoma is a type of aggressive bone cancer that most commonly affects children and young adults between the ages of 10 and 20, during times of rapid bone growth. Although rare, it has a significant impact on young people and their families as treatment can require surgery or amputation.

Study reveals dangerous mutations in H5N1 bird flu

One of the earliest strains of bird flu isolated from a human in Texas shows a unique constellation of mutations that enable it to more easily replicate in human cells and cause more severe disease in mice compared to a strain found in dairy cattle, researchers from Texas Biomedical Research Institute (Texas Biomed) report in Emerging Microbes & Infections.