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Don't Miss Mutation News, Articles and Videos Mutation news, articles and videos from around the web. Read about the latest developments in genetic mutation, cancer mutations, and other health-related topics. Mutation is the process by which a gene or DNA sequence undergoes a change that results in a different phenotype, or physical trait, compared to other individuals in the same species. Mutations can occur naturally, as a result of genetic recombination, or through external agents such as radiation, chemicals, or viruses. Mutations can have both beneficial and harmful effects, and can be the cause of genetic diseases, birth defects, and even cancer. In recent years, scientists have been able to identify and study specific genes that are associated with particular traits, and to understand how mutations in those genes can lead to diseases. This has enabled researchers to develop targeted treatments for certain conditions, such as cancer, and to better understand the role of genes in development and evolution. Stay up to date on the latest news, articles, and videos about mutations from around the web. Learn more about how mutations can affect health, how scientists are using mutational analysis to develop treatments for diseases, and how mutations can help us understand the
Germinal centers are high-speed evolution machines. Tiny clusters in the lymph nodes, germinal centers refine antibodies through mutation and expansion until they produce high-affinity B cells adapted to keep different pathogens in check.
Probing the sphingosine-1-phosphate exporter SPNS2 through an international collaboration of academia and industry, with results reporting a novel high-throughput screening assay, small-molecule targeting of the transporter, and the pathogenic mechanisms of mutations that cause hearing loss.
Enzymes originally evolved in high-temperature environments and later adapted to lower temperatures as Earth cooled. Scientists discovered that a key shift in enzyme function occurred over evolutionary time due to amino acid changes distant from the active site. These mutations lowered activation energy, enhancing catalytic efficiency at low temperatures. Their findings highlight how global cooling events influenced enzyme evolution.
A genetic mutation in horses that would typically halt protein production has become a molecular asset. Researchers at Johns Hopkins University and Vanderbilt University have identified a rare instance of genetic recoding that enhances oxygen metabolism and energy production in horses, donkeys, and zebras.