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Don't Miss Mutation News, Articles and Videos Mutation news, articles and videos from around the web. Read about the latest developments in genetic mutation, cancer mutations, and other health-related topics. Mutation is the process by which a gene or DNA sequence undergoes a change that results in a different phenotype, or physical trait, compared to other individuals in the same species. Mutations can occur naturally, as a result of genetic recombination, or through external agents such as radiation, chemicals, or viruses. Mutations can have both beneficial and harmful effects, and can be the cause of genetic diseases, birth defects, and even cancer. In recent years, scientists have been able to identify and study specific genes that are associated with particular traits, and to understand how mutations in those genes can lead to diseases. This has enabled researchers to develop targeted treatments for certain conditions, such as cancer, and to better understand the role of genes in development and evolution. Stay up to date on the latest news, articles, and videos about mutations from around the web. Learn more about how mutations can affect health, how scientists are using mutational analysis to develop treatments for diseases, and how mutations can help us understand the
Researchers reveal how H5N1 viruses rapidly adapted to mammals through genetic reassortment and specific mutations, raising concerns over potential pandemic risks. Evidence from mink, marine mammals, and dairy cattle shows mammal-to-mammal transmission.
The systematic characterization of azole antifungal resistance mutations in the drug target Erg11 provides an extensive catalog of resistance mutations and reveals that resistance can arise through a large set of mutations that will likely lead to azole pan-resistance without a fitness cost.
We found a bladder cancer family in which germline mutations of POLD1 and somatic mutations of FGFR3 were prevalent. We studied the changes in the immune microenvironment in patients with this mutation in our cohort and a TCGA cohort and predicted the prognosis of patients with this subtype.
Based on the bladder cancer (BLCA) pedigree containing germline mutation of POLD1 found in our last study, we further analyzed the molecular role of POLD1 driving tumorigenesis. We identified POLD1 as a promotor of BLCA via a MYC driven mechanism.
This study is the first report identifying a pathogenic EGFR germline mutation in prostate cancer, suggesting venues for germline screening, non-invasive diagnosis and monitoring in clinical practice.
Each year, roughly the same numbers of boys and girls are born. But in individual families, some couples have four or more daughters and no sons, and some have all male children and no female children, points out University of Michigan evolutionary geneticist Jianzhi Zhang. This has led some scientists to question whether this skewed sex ratio is a result of the genes of the parents.