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1. Scientists Discover Gene Mutation That Causes Brain Cancer In Children, https://www.forbes.com/sites/robinandrews/2017/03/24/scientists-discover-gene-mutation-that-causes-brain-cancer-in-children/#7a0ae1a04a45 2. Genome Editing: What It Is and What It Could Mean for the Future, https://www.technologyreview.com/s/602566/genome-editing-what-it-is-and-what-it-could-mean-for-the-future/ 3. How CRISPR Is Changing Genetics, https://www.nytimes.com/2017/04/06/science/crispr-genetics-genome-editing.html 4. Scientists Add a 33rd Human Chromosome to Cells in the Lab, https://www.the-scientist.com/news-opinion/scientists-add-a-33rd-human-chromosome-to-cells-in-the-lab-67288
The blue wildebeest is a keystone species in savanna ecosystems and is renowned for its spectacular migrations. Despite the ecological importance of the wildebeest, there is a lack of understanding of how its unique migratory ecology has affected its gene flow, genetic structure and phylogeography.
The genetic basis of response to BNT162b2 anti-COVID-19 mRNA vaccine were investigated in 1,351 Italian subjects. Variants in the human leukocyte antigen locus significantly associated with serum anti-SARS-CoV-2 antibody levels, after vaccination.
A deep dive into macroalgae genetics has uncovered the genetic underpinnings that enabled macroalgae, or 'seaweed,' to evolve multicellularity. Three lineages of macroalgae developed multicellularity independently and during very different time periods by acquiring genes that enable cell adhesion, extracellular matrix formation, and cell differentiation, researchers report. Surprisingly, many of these multicellular-enabling genes had viral origins. The study, which increased the total number of sequenced macroalgal genomes from 14 to 124, is the first to investigate macroalgal evolution through the lens of genomics.
A deep dive into macroalgae genetics has uncovered the genetic underpinnings that enabled macroalgae, or "seaweed," to evolve multicellularity. Three lineages of macroalgae developed multicellularity independently and during very different time periods by acquiring genes that enable cell adhesion, extracellular matrix formation, and cell differentiation, researchers report in the journal Molecular Plant.
"This study introduces Cancer-Alterome, a literature-mined dataset that focuses on the regulatory events of an organism’s biological processes or clinical phenotypes caused by genetic alterations. It empowers investigation of cancer pathology, enabling tracking of relevant literature support."
Humans, Homo sapiens, have unique features compared with other closely related hominin species and primates, including the shape of the base of the skull. The evolutionary changes underlying these features were significant in allowing the evolution of our increased brain size.
If evolution was originally depicted as a tree, with different species branching off as new blooms, then new research shows how the branches may actually be more entangled. In "Hybrid speciation driven by multilocus introgression of ecological traits," published in Nature, Harvard researchers show that hybrids between species of butterflies can produce new species that are genetically distinct from both parent species and their earlier forebears.
Researchers have identified a variant in the gene TBX1 as key in the development of the unique morphology at the base of the skull. TBX1 is present at higher levels in humans than in closely related hominins. Low TBX1 also occurs in certain genetic conditions causing altered skull base morphology. This study provides a greater understanding of human disease and evolution.
The origin of life continues to remain a matter of debate. The ribonucleic acid (RNA) world hypothesis proposes that 'ribozymes' which store genetic information and possess catalytic functions may have supported the activities of early life forms. Now, researchers explore how RNA elongation is regulated allosterically, shedding light on its impact on early life processes and offering insights into the fabrication of arbitrary RNA nanostructures with various modern applications.
Animal and plant populations have been extensively studied, which has helped to understand ecosystem processes and evolutionary adaptations. However, this has not been the case with microbial populations due to the impossibility of isolating, culturing and analyzing the genetic content of the different species and their individuals in the laboratory. Therefore, although it is known that populations of microorganisms include a great diversity, this remains largely uncharacterized.